THE BEST SIDE OF SBS88

Some strands of Escherichia coli can include the polyketide synthetase (pks) island that encodes colibactin, a genotoxic compound that could alkylate DNA on adenine residues and induce issue mutations with a particular signature12,13 (COSMIC SBS88). Furthermore, publicity to pks+ E. coli generates a characteristic limited indel signature (COSMIC ID